Clioquinol – CAS 130-26-7 – Calbiochem

Descrição detalhada : A metal ion chelator that crosses the blood brain barrier and acts as a neurotoxic antibiotic. Reported to dissolve senile plaques and reduce amyloid's ability to clump together, apparently by trapping the Cu2+ and Zn2+ that stud these deposits. Shown to increase distal dominant axonopathy in animal models., A metal ion chelator that crosses the blood-brain barrier and acts as a neurotoxic antibiotic. Reported to dissolve senile plaques and reduce amyloid's ability to clump together, apparently by trapping the Cu2+ and Zn2+ that reduces the build-up of these deposits. Exhibits greater affinity for Cu2+ and Zn2+ than for Ca2+ and Mg2+. Shown to induce distal dominant axonopathy in animal models. Clioquinol treatment has been shown to be beneficial in a mouse model of Alzheimer's disease.
Sinónimos : Clioquinol - CAS 130-26-7 - Calbiochem; 5-Chloro-7-iodo-8-hydroxyquinoline
Fórmula molecula r: C9H5ClINO
Armazenamento : -20C
Embalagem : 1X1GM