Goe 6983 – CAS 133053-19-7 – Calbiochem

Descrição detalhada : A potent, cell-permeable, inhibitor of protein kinase C (PKC) that has been shown to selectively inhibit several PKC isozymes (IC50 = 7 nM for PKCalpha and PKCbeta; 6 nM for PKCgamma; 10 nM for PKCdelta; 60 nM for PKCzeta). Goe 6983 does not effectively inhibit PKCµ (IC50 = 20 µM) and can thus be used to differentiate PKCµ from other PKC isozymes., A potent, cell-permeable, reversible, and ATP-competitive inhibitor of protein kinase C (PKC) that inhibits several PKC isozymes (IC50 = 7 nM for PKCalpha and PKCbeta; 6 nM for PKCgamma; 10 nM for PKCdelta; and 60 nM for PKCzeta). Goe 6983 does not effectively inhibit PKCµ (IC50 = 20 µM) and can thus be used to differentiate PKCµ from other PKC isozymes.
Sinónimos : Goe 6983 - CAS 133053-19-7 - Calbiochem; 2-[1-(3-Dimethylaminopropyl)-5-methoxyindol-3-yl]-3-(1H-indol-3-yl) maleimide, Go 6983
Fórmula molecula r: C26H26N4O3
Armazenamento : -20C
Embalagem : 1X500UG