Histone Acetyltransferase Inhibitor IV, CPTH2 – CAS 357649-93-5 – Calbiochem

Descrição detalhada : A cell-permeable thiazolyl-hydrazone compound that inhibits the acetylation of histone H3 by recombinant human Gcn5 in a substrate-competive manner, while exhibiting little activity against rhGcn5 autoacetylation. Although functional knockout of Gcn5 in Saccharomyces cerevisiae by genetic deletion or by CPTH2 treatment is not detrimental to the survival of the budding yeast, CPTH2 treatment is shown to inhibit the growth of yeast strain genetically deleted of Gcn5, but not strains deleted of Elp3 or Sas2.
Sinónimos : Histone Acetyltransferase Inhibitor IV, CPTH2 - CAS 357649-93-5 - Calbiochem; HAT Inhibitor IV, Cyclopentylidene-(4-(4?-chlorophenyl)thiazol-2-yl)hydrazone, GCN5 Inhibitor II, N-acetyltransferase 10 Inhibitor I, NAT10 Inhibitor I
Fórmula molecula r: C14H14ClN3S
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG