InSolution IKK-2 Inhibitor IV – Calbiochem

REF : 401484-500UG
Marca : Sigma-Aldrich
Descrição :InSolution IKK-2 Inhibitor IV - Calbiochem The InSolution IKK-2 Inhibitor IV controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
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Descrição detalhada : IKK-2 Inhibitor IV (Cat. No. 401481) supplied in DMSO. A cell-permeable and potent inhibitor of IKK-2 (IC50 = 18 nM) that exhibits selectivity over IKK-1, JNK, and p38 MAPK. Inhibits TNF-alpha production in human monocytes (IC50 in the range of 0.15-2.5 µM) and blocks IL-8 and IL-6 production by synovial fibroblasts (IC50 = 100 nM). Shown to reduce paw oedema in rat arthritis model (~100% inhibition at a dose of 30 mg/kg).
Sinónimos : InSolution IKK-2 Inhibitor IV - Calbiochem
Fórmula molecula r: C12H10FN3O2S
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X500UG