Pepstatin A Methyl Ester – Calbiochem

Descrição detalhada : A cell-permeable methyl ester derivative of Pepstatin A (Cat. No. 516482) that acts as a potent, non-competitive, transition-state analog inhibitor of gamma-secretase (Kis = 15 nM and Kii = 32 nM in solubilized human gamma-secretase; Kis is the inhibition constant for inhibitor binding to the free enzyme and Kii is the inhibition constant for inhibitor binding to the Enzyme-Substrate complex)., A cell-permeable methyl ester derivative of Pepstatin A (Cat. No. 516481) that acts as a potent, non-competitive, transition-state analog inhibitor of γ-secretase (Kis = 150 nM, Kii = 320 nM in solubilized human γ-secretase at 20C; Kis is the inhibition constant for inhibitor binding to the free enzyme and Kii is the inhibition constant for inhibitor binding to the Enzyme-Substrate complex). Sta = (3S,4S)-4-Amino-3-hydroxy-6-methyl-heptanoic acid.
Sinónimos : Pepstatin A Methyl Ester - Calbiochem; Isovaleryl-V V-Sta-A-Sta-OCH?, PME
Fórmula molecula r: C35H65N5O9
Armazenamento : -20C
Embalagem : 1X1MG