Riluzole – CAS 1744-22-5 – Calbiochem

Descrição detalhada : A cell-permeable benzothiazole compound that potently inhibits glutamate release and blocks Na+ channels. Reported to function as a polyglutamine aggregation inhibitor and stimulate the synthesis of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and glial cell-derived neurotrophic factor (GDNF) in mouse astrocyte cultures. Offers neuroprotection, slows disease progression in amyotrophic lateral sclerosis (ALS) patients, and prolongs survival in animal models of Huntington's disease (HD)., A cell-permeable benzothiazole compound that potently inhibits glutamate release and blocks Na+ channels. Shown to function as a polyglutamine aggregation inhibitor and stimulates the synthesis of NGF, BDNF, and GDNF in mouse astrocyte cultures. Reported to offer neuroprotection, slow down disease progression in ALS (amyotrophic lateral sclerosis) patients, and prolong the lifespan of animal models of HD (Huntington's disease).
Sinónimos : Riluzole - CAS 1744-22-5 - Calbiochem; 2-Amino-6-(trifluoromethoxy)benzothiazole, PK 26124
Fórmula molecula r: C8H5F3N2OS
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X50MG