InSolution STAT3 Inhibitor III, WP1066 – Calbiochem

REF : 573129-5MG
Marca : Sigma-Aldrich
Descrição :InSolution STAT3 Inhibitor III, WP1066 - Calbiochem The InSolution STAT3 Inhibitor III, WP1066, also referenced under CAS 857064-38-1, controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable AG 490 (Cat. No. 658401) tyrphostin analog that acts as an effective STAT3 pathway inhibitor and a much more potent antitumor agent than AG 490 in inhibiting malignant glioma growth both in cultures in vitro (IC50 = 5.6 and 3.7 µM in a viability assay using U87-MG and U373-MG, respectively; no inhibition against nontumor NHA at 10 µM) and in mice in vivo. Shown to cross blood-brain barrier in mice in vivo.
Sinónimos : InSolution STAT3 Inhibitor III, WP1066 - Calbiochem
Fórmula molecula r: C17H14BrN3O
Armazenamento : -20C
Embalagem : 1X5MG