AG 1295 – CAS 71897-07-9 – Calbiochem

REF : 658550-5MG
Marca : Sigma-Aldrich
Descrição :AG 1295 - CAS 71897-07-9 - Calbiochem A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC?? = 500 nM) and PDGF-dependent DNA synthesis (IC?? = 2.5 µM) in Swiss/3T3 cells.
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Descrição detalhada : A cell-permeable, reversible, ATP-competitive, and selective inhibitor of platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500 nM) and PDGF-dependent DNA synthesis (IC50 = 2.5 µM) in Swiss/3T3 cells. Has no effect on EGF receptor autophosphorylation and shows only a weak effect on EGF- or insulin-stimulated DNA synthesis. A potent blocker of smooth muscle cell proliferation., Selectively inhibits platelet-derived growth factor (PDGF) receptor kinase (IC50 = 500 nM) and the PDGF-dependent DNA synthesis (IC50 = 2.5 µM) in Swiss 3T3 cells. Has no effect on epidermal growth factor (EGF) receptor autophosphorylation and shows only a weak effect on EGF- or insulin-stimulated DNA synthesis.
Sinónimos : AG 1295 - CAS 71897-07-9 - Calbiochem; 6,7-Dimethyl-2-phenylquinoxaline
Fórmula molecula r: C16H14N2
Armazenamento : -20C
Embalagem : 1X5MG