AG 126 – CAS 118409-62-4 – Calbiochem

Descrição detalhada : A cell-permeable inhibitor of lipopolysaccaride (LPS)-induced synthesis of tumor necrosis factor-alpha and nitric oxide in murine peritoneal macrophages. Blocks LPS-induced tyrosine phosphorylation of a p42MAPK protein substrate., A cell-permeable inhibitor of lipopolysaccharide (LPS)-induced synthesis of tumor necrosis factor-alpha and nitric oxide in murine peritoneal macrophages. Blocks LPS-induced tyrosine phosphorylation of a p42MAPK/ERK2 protein substrate. Reduces the expression of iNOS and COX-2 in lungs of rats treated with carrageenan. Blocks glucocorticoid-induced COX-2 activity in human amnion cells (IC50 = 15.38 µM).
Sinónimos : AG 126 - CAS 118409-62-4 - Calbiochem; alpha-Cyano-(3-hydroxy-4-nitro)cinnamonitrile
Fórmula molecula r: C10H5N3O3
Armazenamento : -20C
Embalagem : 1X5MG