Anti-Fmc-7 (B-Cell Lymphocyte Marker), clone Fmc-7 Antibody

REF : MAB1217-I
Marca : Sigma-Aldrich
Descrição :Anti-Fmc-7 (B-Cell Lymphocyte Marker), clone Fmc-7 Antibody clone Fmc-7, from mouse
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Descrição detalhada : B cells are lymphocytes that play a large role in the humoral immune response as opposed to the cell-mediated immune response that is governed by T cells. The principal function of B cells is to make antibodies against soluble antigens. B cells are an essential component of the adaptive immune system. FMC-7 B-Cell Lymphocyte Marker is a 105 kDa B cell restricted antigen which is expressed on about 50% of adult human peripheral blood B cells. Upon in vivo B cell activation FMC7 expression initially increases. B cells involved in antibody secretion have lost the FMC7 determinant. The monoclonal antibody FMC7 delineates a subpopulation of B lymphocytes in normal blood. Expression of the antigen recognized by FMC7 appears to be maturation-linked, and it serves to distinguish different types of B cell leukemia.
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA