AKR1C1 Inhibitor, 5-PBSA – CAS 4906-68-7 – Calbiochem

REF : 123850-25MG
Marca : Sigma-Aldrich
Descrição :AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem The AKR1C1 Inhibitor, 5-PBSA, also referenced under CAS 4906-68-7, controls the biological activity of AKR1C1.
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Descrição detalhada : A cell-permeable salicylic acid compound that acts as a highly potent, active-site directed and substrate competitive AKR1C1 inhibitor (Ki = 4 nM) with moderate to excellent selectivity over AKR1C2, AKR1C3 and AKR1C4 (Ki = 0.087, 4.2 and 18.2 µM, respectively). Shown to inhibit the metabolism of progesterone by AKR1C1 (IC50 = 460 nM in AKR1C1 overexpressing BAECs).
Sinónimos : AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem; Aldo-Keto Reductase family 1 member C1 Inhibitor, 5-PBSA, 3-Bromo-5-phenylsalicylic acid, 20alpha-Hydroxysteroid Dehydrogenase Inhibitor, 5-PBSA
Fórmula molecula r: C13H9BrO3
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X25MG