Angiotensin Converting Enzyme-2, His.Tag(R), Human, Recombinant, NSO Cells

REF : 176872-10UG
Marca : Sigma-Aldrich
Categoria :
Descrição detalhada : Recombinant, human ACE-2 ectodomain (amino acids 1-740) fused at the C-terminus to a His.Tag sequence and expressed in NSO cells. ACE-2 cleaves angiotensins I and II as a carboxypeptidase and plays an important role in regulating cardiovascular and renal functions. Native ACE-2 is an integral membrane zinc metalloprotease whose activity is inhibited by EDTA. By SDS-PAGE, the apparent molecular mass of the glycosylated protein is ~120 kDa under either reducing or non-reducing conditions., Recombinant, human ACE-2 ectodomain (amino acids 1-740) fused at the C-terminus to a His.Tag sequence and expressed in NSO cells. Native ACE-2 is an integral membrane zinc metalloprotease that can be inhibited by EDTA. ACE-2 cleaves angiotensins I and II. Plays an important role in regulating cardiovascular and renal functions. By SDS-PAGE, the apparent molecular mass of the glycosylated protein is ~120 kDa under either reducing or non-reducing condition.
Sinónimos : ACE Homolog, ACEH, ACE-2
Armazenamento : -70C
Embalagem : 1X10UG