Anthrax Lethal Factor Protease Inhibitor, In-2-LF – Calbiochem

REF : 176901-1MG
Marca : Sigma-Aldrich
Descrição :Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem The Anthrax Lethal Factor Protease Inhibitor, In-2-LF controls the biological activity of Anthrax Lethal Factor Protease. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
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Descrição detalhada : A cell-permeable N-acetylated, C-hydroxamate derivative of a 14-mer peptide designed from the MEK-2 template that acts as a competitive inhibitor of Anthrax lethal factor (LF) metalloprotease (Ki = 1 nM). Also inhibits MEK-3 cleavage. Protects against Anthrax toxin induced cytotoxicity in RAW264.7 and J772.A1 cells., A cell-permeable derivative of a 14-mer peptide that is based on the MEK-2 template and acts as a competitive inhibitor of Anthrax lethal factor metalloprotease (Ki = 1 nM). Also inhibits MEK-3 cleavage. Exhibits protective effects against Anthrax toxin-induced cytotoxicity in RAW264.7 and J772.A1 cells. Reported to competitively inhibit furin (Ki = 49 nM.
Sinónimos : Anthrax Lethal Factor Protease Inhibitor, In-2-LF - Calbiochem; Anthrax LF Protease Inhibitor, Bacillus anthracis LF Protease Inhibitor, In-2-LF; Anthrax LF Protease Inhibitor, Bacillus anthracis LF Protease Inhibitor, In-2-LF
Fórmula molecula r: C81H150N42O17
Armazenamento : -20C
Embalagem : 1X1MG