Anti-DPPA-2 Antibody, clone 6C1.2

Descrição detalhada : DPPA-2 (developmental pluripotency associated-2) is a novel Oct-4-related protein that is localized to the nucleus of mouse fetal germ cells. DPPA-2 has binding sites for both POU and Sox-2 protein domains and is expressed primarily in the developing germ line following gastrulation. These associations suggest that this protein participates in a very strong supportive role in maintaining cell pluripotentiality. In addition to its role as a pluripotency marker, more recent research using cancer cells suggests that DPPA-2 may also act as an embryo-cancer antigen-pointing to the presence of abnormal cell growth and the formation of cancerous cells.
Sinónimos : Pluripotent embryonic stem cell-related gene 1 protein, developmental pluripotency associated 2
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA