Anti-JMJD4 (NT) Antibody

Descrição detalhada : Covalent modification of histones plays critical role in regulating chromatin structure and transcription. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that remove specific methyl marks from histones. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed. JMJD4 is a transcription factor that is a putative histone demethylase. It is highly expressed in lymphoid (spleen) and hemopoietic (bone marrow) tissues
Sinónimos : JMJD, Jumonji domain-containing protein 4, jumonji domain containing 4
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA