Anti-Histone Antibody, Pan, clone F152.C25.WJJ

Descrição detalhada : This antibody detects histone H1 and nuclesomal core proteins histones H2a, H2b, H3, H4. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.Histone H1 is a nuclear protein necessary for condensation of nucleosome chains into higher order structures.
Sinónimos : Histone H1.4, Histone H1b
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA