Anti-PTIP Antibody

Descrição detalhada : PAX transactivation activation domain-interacting protein (PTIP) is a ubiquitous nuclear protein composed of 5 tandem BRCA1 carboxyl-terminal (BRCT) domains. PTIP was initially identified as an interacting, transactivation protein that binds to the C-terminal end of Pax2. Since its discovery, studies have shown PTIP to bind several Pax proteins, playing a critical role in response to DNA damage. It also has activity as a phosphoserine/ phosphothreonine-specific binding module, and can discern ATM and ATR gamma irradiation induced phosphorylated substrates. PTIP is involved in early cellular development and is likely to have a role in cell proliferation as well.
Sinónimos : PAX interacting (with transcription-activation domain) protein 1, PAX transactivation activation domain-interacting protein, protein encoded by CAG trinucleotide repeats, PAX transcription activation domain interacting protein 1 like
Armazenamento : +2°C to +8°C
Embalagem : 1X1EA