gamma-Secretase Substrate, Fluorogenic – Calbiochem

Descrição detalhada : An internally quenched fluorogenic peptide substrate containing the C-terminal beta-APP (amyloid beta-peptide precursor protein) amino acid sequence that is cleaved by gamma-secretase. Shown to be sensitive and useful for assaying gamma-secretase activity. The proteolysis at the Abeta40-, Abeta42-, and Abeta43-generating cleavage sites results in enhanced fluorescence. Excitation max.: ~355 nm; emission max.: ~440 nm., An internally quenched fluorogenic peptide substrate containing the C-terminal beta-APP (amyloid beta-peptide precursor protein) amino acid sequence that is cleaved by gamma-secretase. Shown to be sensitive and useful for assaying gamma-secretase activity. The proteolysis at the Abeta40-, Abeta42-, and Abeta43-generating cleavage sites results in enhanced fluorescence.
Sinónimos : gamma-Secretase Substrate, Fluorogenic - Calbiochem; NMA-GGVVIATVK(DNP)- DR DR DR-NH₂
Fórmula molecula r: C70H116N26O18
Armazenamento : -20C
Embalagem : 1X1MG