JAK2 Inhibitor III, SD-1029
REF : 573098-10MG
Marca : Sigma-Aldrich
Descrição :JAK2 Inhibitor III, SD-1029 The JAK2 Inhibitor III, SD-1029, also referenced under CAS 118372-34-2, controls the biological activity of JAK2.
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Categoria : Small Molecules
Descrição detalhada : A cell-permeable xanthenedione compound that acts as a JAK2-selective inhibitor. It exhibits much less effect on the cellular phosphorylation levels of Jak1 and Src and shows no significant inhibition towards a panel of 49 other protein kinases in cell-free kinase assays at a concentration of 10 µM. Effectively inhibits cell proliferation in JAK-activated BA/F3 cell lines as well as phosphorylation and nuclear translocation of cellular Stat3.
Sinónimos : JAK2 Inhibitor III, SD-1029; 9-(3,4-Dichlorophenyl)-2,7-bis(dimethylaminomethyl)-3,4,5,6,7,9-hexahydro-2H-xanthene-1,8-dione, 2HBr, NSC 371488
Fórmula molecula r: C25H30Cl2N2O3 · 2HBr
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG
Sinónimos : JAK2 Inhibitor III, SD-1029; 9-(3,4-Dichlorophenyl)-2,7-bis(dimethylaminomethyl)-3,4,5,6,7,9-hexahydro-2H-xanthene-1,8-dione, 2HBr, NSC 371488
Fórmula molecula r: C25H30Cl2N2O3 · 2HBr
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X10MG