Monoclonal Anti-S-100 (beta-Subunit) antibody produced in mouse

Descrição detalhada : S100B (S-100? Subunit) belongs to the S100 family of calcium-binding proteins. It is expressed in melanocytes. S-100 is a set of small, thermolabile, highly acidic dimer proteins of approximately 20kDa which are widely distributed in different tissues. Dimeric combinations of two chains, the ?-chain (93 amino acids,10.4kDa) and the ?-chain (91 amino acids, 10.5kDa), form the three known subtypes of S-100: S-100ao (??), S-100a (??) and S-100b (??).Monoclonal Anti-S-100 (?-subunit) (mouse IgG1 isotype) is derived from the SH-B1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse., S100 gene is mapped on human chromosome 21q22.3 and codes for an acidic calcium binding protein B, which weighs 21 kDa. The gene is predominantly expressed in astrocytes, glial cells, Schwann cells and also found in adipose cells, skin, glioblastoma multiforme and melanoma. The protein is localized in extracellular space and cytoplasm.
Sinónimos : Anti-NEF; Anti-S100; Anti-S100-B; Anti-S100beta
Armazenamento : -20C
Embalagem : 1X.2ML