OECM-1 Human Oral Squamous Carcinoma Cell Line

Descrição detalhada : Squamous cell carcinoma (SCC) is a common cancer type, developing in epithelial cells. Nearly all cancers of the oral cavity are squamous cell carcinomas, and the high recurrence rate among oral SCCs make these challenging targets for therapies. Established models of this cancer type continue to yield significant insights into the properties and potential treatments of head and neck cancers ., The OECM-1 human oral cavity squamous cell carcinoma cell line is a well-established model for squamous cell carcinoma. The OECM-1 cell line harbors a missense mutation in the p53 tumor suppressor , displays low EGFR expression , and is tumorigenic in nude mice . OECM-1 cells proliferate with a doubling time of 30-38 hours and are capable of anchorage-independent growth, forming spheroid colonies . OECM-1 cells have been intensively characterized in the literature for morphology, biomarker expression and drug response .Source:The OECM-1 human oral cavity squamous cell carcinoma cell line was derived from surgical resection of a primary tumor of a Taiwanese male patient .
Sinónimos : OECM1, OEC-M1
Armazenamento : -140C Degree Freezer
Embalagem : 1X1EA