Protein Arginine N-Methyltransferase Inhibitor, AMI-1 – Calbiochem

REF : 539209-5MG
Marca : Sigma-Aldrich
Descrição :Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem The Protein Arginine N-Methyltransferase Inhibitor, AMI-1 controls the biological activity of Protein Arginine N-Methyltransferase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
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Descrição detalhada : A cell-permeable, symmetrical sulfonated urea compound that acts as a potent, specific and non-AdoMet (S-adenosyl-L-methionine, SAM)-competitive inhibitor of protein arginine N-methyltransferases (PRMTs; IC50 = 8.81 µM for PRMT1 and 3.03 for yeast-RMT1p) with minimal effect on lysine methyltransferases. Inhibits nuclear receptor reporter gene activation in MCF-7 cells, and HIV-1 RT polymerase (IC50 = 5 µM).
Sinónimos : Protein Arginine N-Methyltransferase Inhibitor, AMI-1 - Calbiochem; PRMT Inhibitor I
Fórmula molecula r: C21H12N2Na4O9S2
Armazenamento : -20C
Embalagem : 1X5MG