TGF-beta 3-E. coli human

Descrição detalhada : The gene TGF-?3 (transforming growth factor ? 3) is mapped to human chromosome 14q24.3. The three mammalian isoforms of TGF-?, TGF-?1, ?2, ?3 elicit similar biological responses. TGF-? proteins are made as precursor molecules which are cut to generate a mature carboxy-terminal region of 110-140 amino acids. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-? isoform from a latent complex involves proteolytic processing of the complex and/or induction of conformational changes by proteins such as thrombospondin-1. Recombinant TGF-?3 is a 25.0kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
Sinónimos : Transforming Growth Factor-beta3
Armazenamento : -20C
Embalagem : 1X10UG