Thrombomodulin human

REF : SRP3172-10UG
Marca : Sigma-Aldrich
Descrição :Thrombomodulin human recombinant, expressed in HEK 293 cells, >=98% (SDS-PAGE), >=98% (HPLC), suitable for cell culture
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Descrição detalhada : Thrombomodulin is an integral membrane protein that spans a length of 559 residues and contains five structural domains. The hydrophobic amino terminal domain is made up of 223 amino acid residues. The adjacent domain contains six EGF type B repeats spanning a length of 236 residues. This is followed by a 34 amino acid-long Ser/Thr-rich domain, which may be involved in 0-linked glycosylation. The next domain is a putative membrane-spanning domain of 23 residues, followed by a carboxyl-terminal cytosolic tail of 38 residues. The gene encoding this protein lacks introns. Recombinant soluble thrombomodulin is a 491 amino acid glycoprotein containing the extracellular domain of thrombomodulin.
Sinónimos : BDCA-3; CD141; THBD; TM
Armazenamento : -20C
Embalagem : 1X10UG