Vigabatrin – CAS 68506-86-5 – Calbiochem

Descrição detalhada : A selective, irreversible inhibitor of GABA transaminase with antiepileptic properties. Covalently binds to the active site of GABA tansaminase to inactivate it in a dose-dependent manner and increases extracellular GABA levels in the brain. Rapidly absorbed following oral administration and is shown to inhibit [3H]GABA uptake across the apical membrane of Caco-2 cell monolayers in a concentration-dependent manner (IC50 = 2.9 mM)
Sinónimos : Vigabatrin - CAS 68506-86-5 - Calbiochem; 4-Amino-5-hexenoic acid, GABA Transaminase Inhibitor, Vigabatrin, gamma-Vinyl-GABA, Sabril
Fórmula molecula r: C6H11NO2
Armazenamento : 2-8C; 2-8C
Embalagem : 1X1EA