Wnt Agonist I in DMSO – CAS 853220-52-7 – Calbiochem

REF : 681664-2MG
Marca : Sigma-Aldrich
Descrição :Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
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Descrição detalhada : A cell-permeable, potent, and selective activator of Wnt signaling that does not inhibit the activity of GSK-3beta (IC50 >60 µM). Shown to mimic the effect of Wnt and induce beta-catenin and TCF (T-cell fate)-dependent transcriptional activity (EC50 = 700 nM in HEK-293T cells). Reported to cause substantial head defects during Xenopus embryonic development. The solid form of this compound (Cat. No. 681665) is also available.
Sinónimos : Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem; 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine, Wnt Pathway Activator I in DMSO; Wnt Pathway Activator I in DMSO, 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine
Fórmula molecula r: C19H18N4O3
Armazenamento : -70C
Embalagem : 1X2MG