HIF Inhibitor VI – Calbiochem

REF : 400086-5MG
Marca : Sigma-Aldrich
Descrição :HIF Inhibitor VI - Calbiochem The HIF-1 Inhibitor, NSC-134754 controls the biological activity of HIF-1. This small molecule/inhibitor is primarily used for Cell Structure applications.
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Descrição detalhada : A cell-permeable emetan derivative that selectively reduces HIF-1 activity by 73% in a luciferase reporter assay, and blocks HIF-1alpha protein induction in response to DFX, hypoxia, and IGF-1 in U2OS-HRE-luc cells at 10 µM, without significantly inhibiting cell growth. Furthermore, it is shown to completely block HIF-1alpha induced by IGF-1 in HCT116 human colon carcinoma cells.
Sinónimos : HIF Inhibitor VI - Calbiochem; NSC-134754
Fórmula molecula r: C27H34N2O2
Armazenamento : 2-8C; 2-8C; 2-8C
Embalagem : 1X5MG