TGF-beta RI Kinase Inhibitor III – CAS 356559-13-2 – Calbiochem

REF : 616453-2MG
Marca : Sigma-Aldrich
Descrição :TGF-beta RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem The TGF-beta RI Kinase Inhibitor III, also referenced under CAS 356559-13-2, controls the biological activity of TGF-beta RI Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
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Descrição detalhada : A cell-permeable imidazolyl-pyridine compound that acts as a potent, ATP-competitive, reversible, and selective inhibitor of activin receptor-like kinase 4 (IC50 = 129 nM), 5 ( IC50 = 47 nM), and 7. It inhibits p38 MAPKalpha only at much higher concentrations (IC50 = 10.6 µM) and has little effect against ALK1/2/3/6 as well as a panel of 26 other kinases.
Sinónimos : TGF-beta RI Kinase Inhibitor III - CAS 356559-13-2 - Calbiochem; Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor III, 2-(5-Benzo[1,3]dioxol-4-yl-2-tert-butyl-1H-imidazol-4-yl)-6-methylpyridine, HCl, ALK5 Inhibitor III, SB-505124, HCl
Fórmula molecula r: C20H21N3O2 · xHCl
Armazenamento : 2-8C; 2-8C; 2-8C; 2-8C
Embalagem : 1X2MG